FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4GMR53C10
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General Information
Symbol
Scer\GAL4GMR53C10
Species
S. cerevisiae
Name
FlyBase ID
FBal0253371
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR53C10-GAL4}
Also Known As
R53C10
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR53C10-GAL4}
Cytology
Description

A 2784 base pair fragment from the flanking non-coding or intronic region of 5-HT1A is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR53C10
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      gorget | restricted
      (Jenett and Svirskas, 2012.9.24)
      adult brain | restricted
      (Shuai et al., 2015)
      mushroom body extrinsic neuron
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 1
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 2
      (Shuai et al., 2015)
      mushroom body gamma lobe slice 4
      (Shuai et al., 2015)
      mushroom body beta lobe slice 1
      (Shuai et al., 2015)
      mushroom body beta' lobe slice 2
      (Shuai et al., 2015)
      mushroom body alpha lobe slice 1
      (Shuai et al., 2015)
      mushroom body alpha lobe slice 2
      (Shuai et al., 2015)
      mushroom body alpha lobe slice 3
      (Shuai et al., 2015)
      Additional Information
      Statement
      Reference

      ScerGAL4GMR53C10 drives expression in mushroom body extrinsic neurons that innervate mushroom body gamma lobe slices 1, 2 and 4, mushroom body beta lobe slice 1, mushroom body beta' lobe slice 2 and mushroom body alpha lobe slices 1, 2 and 3.

      (Shuai et al., 2015)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Hsap\KCNJ2UAS.EGFP) of Scer\GAL4GMR53C10 neurons, in combination with a Gal80[ts] transgene to restrict expression to 1 day prior to training and testing, does not affect 3 hour aversive olfactory memory, compared to controls.

      (Shuai et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR53C10
      Name Synonyms
      Secondary FlyBase IDs
        References (5)