A 1305 base pair fragment from the flanking non-coding or intronic region of foxo is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.
Thermogenetic activation (using TrpA1UAS.(B).cKa at 30[o]C) of Scer\GAL4GMR56C09 cells in adult males significantly increases wing extensions towards females, compared to controls.