FB2021_02, released April 13, 2021

Allele: Scer\GAL4GMR58H01

Open Close
General Information
Symbol
Scer\GAL4GMR58H01
Species
S. cerevisiae
Name
FlyBase ID
FBal0253748
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR58H01-GAL4}
Also Known As
GMR58H01-Gal4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Pfeiffer et al., 2011.2.9)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{GMR58H01-GAL4}
      Cytology
      Nature of the lesion
      Statement
      Reference

      A 3100 base pair fragment from the flanking non-coding or intronic region of Frq1 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

      (Pfeiffer et al., 2011.2.9)
      Allele components
      Product class / Tool use(s)
      Encoded product / tool
      GAL4
      Associated Sequence Features
      GMR58H01
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult gnathal ganglion | faint | restricted
      (Jenett and Svirskas, 2012.9.24)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus with 617 nm (red) light) of Scer\GAL4GMR58H01 cells in adults results in induction of proboscis retraction due to stimulation during feeding, compared to controls.

      (Zhou et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR58H01
      Name Synonyms
      Secondary FlyBase IDs
        References (3)