FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4GMR67E06
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General Information
Symbol
Scer\GAL4GMR67E06
Species
S. cerevisiae
Name
FlyBase ID
FBal0254193
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR67E06-GAL4}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR67E06-GAL4}
Cytology
Description

A 3899 base pair fragment from the flanking non-coding or intronic region of Fmrf is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR67E06
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 29[o]C) of Scer\GAL4GMR67E06 cells in adults significantly reduces the number of animals capable of flight, compared to controls; animals that do not fly have significant wing coordination defects, compared to controls; there is also a significant reduction in the duration of electrophysiological spiking in dorsal longitudinal indirect flight muscles in response to an air puff, compared to controls.

      Inhibition (using Hsap\KCNJ2UAS.EGFP) of Scer\GAL4GMR67E06 cells, in combination with a Gal80[ts] transgene to restrict expression to the adult stage, significantly reduces the number of animals capable of flight, compared to controls; there is also a significant reduction in the number of animals that display electrophysiological spiking in dorsal longitudinal indirect flight muscles in response to an air puff, compared to controls; there are no defects in courtship behavior or copulation latency, compared to controls.

      (Sadaf et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR67E06
      Name Synonyms
      Secondary FlyBase IDs
        References (2)