FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4GMR92H07
Open Close
General Information
Symbol
Scer\GAL4GMR92H07
Species
S. cerevisiae
Name
FlyBase ID
FBal0256100
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR92H07-GAL4}
Also Known As
R92H07
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR92H07-GAL4}
Cytology
Description

A 2096 base pair fragment from the flanking non-coding or intronic region of CG31345 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR92H07
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      anterior optic tubercle | intense | restricted
      (Jenett and Svirskas, 2012.9.24)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Thermogenetic activation (using TrpA1UAS.(B).cKa at [o]C) of Scer\GAL4GMR92H07 cells in adults significantly increases daytime and nighttime sleep, compared to controls; there is also a significant negative rebound on the day following activation, characterised by reduced sleep, compared to controls; activation results in strongly reduced spontaneous walking velocity, compared to controls; initial startle response to stimulation by vibration is unaffected, but the increased velocity decays significantly more rapidly, compared to controls.

      Inhibition (using shi1.UAS at 31[o]C) of Scer\GAL4GMR92H07 cells results in a subtle reduction in daytime sleep and a significant reduction in the duration of the longest sleep bout during the day, but not during the night, compared to controls.

      (Lamaze et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR92H07
      Name Synonyms
      Secondary FlyBase IDs
        References (5)