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General Information
Symbol
Dmel\Pi3K59FHMS00261
Species
D. melanogaster
Name
FlyBase ID
FBal0257161
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Vps34 RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Third instar larvae expressing Pi3K59FHMS00261 under the combined control of Scer\GAL4sca.PU and Scer\GAL4C57 do not show apparent defects in neurotransmission across the neuromuscular junctions (mEPSP and EPSP amplitudes, and quantal content), as compared to controls.

Expression of Pi3K59FHMS00261 under the control of Scer\GAL4Myo31DF-NP0001 results in defective midgut degradation after pupariation, with significantly increased size of the gastric caeca 4 hrs after puparium formation, and significantly decreased autophagy levels 2 hrs after puparium formation, as compared to controls.

Expression of Pi3K59FHMS00261 under the control of Scer\GAL4cg.PU results in a decrease in starvation-induced autophagy in the larval fat body, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Pi3K59FHMS00261
Vps34HMS00261
Name Synonyms
Secondary FlyBase IDs
    References (5)