Vps34, PI3K, dPI3K, PI3K_59F, PI3K-59F
regulates intracellular vesicular transport of proteins at distinct membrane domains through production of phosphatidylinositol-3-phosphate - interacts with Rabenosyn-5 which carries out a subset of Pi3K59 functions - promotes autophagy and endocytosis
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pi3K59F using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pi3K59F in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Pi3K59F CG5373
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Identified by PCR using degenerate primers based on regions of strong amino acid homology found within the putative lipid kinase domain of mammalian p110α and yeast Vps34p.