FlyBase Allele Report: Dmel\ERp60[HMS00885]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\ERp60^HMS00885

General Information

Symbol

Dmel\ERp60^HMS00885

Species

D. melanogaster

Name

FlyBase ID

FBal0257560

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00885}

Key Links

Genomic Maps

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00885}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased cell number | adult stage, with Scer\GAL4^esg.PU

(Makdissi et al., 2025)

increased cell death | adult stage, with Scer\GAL4^esg.PU

(Makdissi et al., 2025)

Phenotype Manifest In

adult posterior midgut, with Scer\GAL4^esg.PU

(Makdissi et al., 2025)

intestinal stem cell of posterior adult midgut epithelium | decreased number, with Scer\GAL4^esg.PU

(Makdissi et al., 2025)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

ERp60^HMS00885, Scer\GAL4^esg.PU is a suppressor of increased cell number | adult stage phenotype of Pex5^GD14972, Scer\GAL4^esg.PU

(Makdissi et al., 2025)

ERp60^HMS00885, Scer\GAL4^esg.PU is a suppressor of short lived | male phenotype of Pex5^GD14972, Scer\GAL4^esg.PU

(Makdissi et al., 2025)

Phenotype Manifest In

Suppressor of

Statement

Reference

ERp60^HMS00885, Scer\GAL4^esg.PU is a suppressor of intestinal stem cell of posterior adult midgut epithelium | increased number phenotype of Pex5^GD14972, Scer\GAL4^esg.PU

(Makdissi et al., 2025)

ERp60^HMS00885, Scer\GAL4^esg.PU is a suppressor of adult gut | male phenotype of Pex5^GD14972, Scer\GAL4^esg.PU

(Makdissi et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

33935

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00885}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ERp60^HMS00885

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections