FlyBase Allele Report: Dmel\EMC1[HMS01055]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\EMC1^HMS01055

General Information

Symbol

Dmel\EMC1^HMS01055

Species

D. melanogaster

Name

FlyBase ID

FBal0257719

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01055}

Key Links

Genomic Maps

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01055}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of cerebellar atrophy, visual impairment, and psychomotor retardation

CEA

(Couto-Lima et al., 2024)

model of intestinal cancer

CEA

(Shi et al., 2023)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult enteroendocrine cell | decreased number, with Scer\GAL4^{Delta-05151-G}

(Shi et al., 2023)

adult enteroendocrine cell | increased number, with Scer\GAL4^esg.PU

(Shi et al., 2023)

adult midgut, with Scer\GAL4^{Delta-05151-G}

(Shi et al., 2023)

adult midgut, with Scer\GAL4^esg.PU

(Shi et al., 2023)

adult midgut, with Scer\GAL4^NP0001

(Shi et al., 2023)

enteroblast | adult stage | increased number, with Scer\GAL4^esg.PU

(Shi et al., 2023)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

EMC1^HMS01055, Scer\GAL4^esg.PU has increased cell number | adult stage phenotype, suppressible by hpo^{UAS.WT.Tag:FLAG}, Scer\GAL4^esg.PU

(Shi et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

EMC1^HMS01055, Scer\GAL4^esg.PU has adult midgut phenotype, suppressible by hpo^{UAS.WT.Tag:FLAG}, Scer\GAL4^esg.PU

(Shi et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

EMC1^HMS01055 is rescued by EMC1^UAS.Tag:FLAG/Scer\GAL4^esg.PU

(Shi et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

34581

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01055}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG2943^HMS01055

EMC1^HMS01055

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections