FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Pi3K68DUAS.mCherry
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General Information
Symbol
Dmel\Pi3K68DUAS.mCherry
Species
D. melanogaster
Name
FlyBase ID
FBal0258485
Feature type
allele
Associated gene
Dmel\Pi3K68D
Associated Insertion(s)
Carried in Construct
P{UAS-mCherry-Pi3K68D}
Also Known As
UAS-mCherry:Pi3K68D
Key Links
Transgenic product class
wild_type
(Velichkova et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Velichkova et al., 2010)
Mutagen
in vitro construct
(Velichkova et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-mCherry-Pi3K68D}
Cytology
Description

UAS regulatory sequences drive expression of Pi3K68D which is tagged at the N-terminal end with mCherry.

(Velichkova et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Pi3K68D
Tagged with
mCherry
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Pi3K68DScer\UAS.T:Disc\RFP-mCherry under the control of Scer\GAL4He.PZ results in hemocytes exhibiting abnormally enlarged endolysosomal compartments.

      (Pueyo et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of hemoScer\UAS.FL or 14-3-3ζGD16467 rescues the increased endolysosomal compartment phenotype of hemocytes expressing Pi3K68DScer\UAS.T:Disc\RFP-mCherry under the control of Scer\GAL4He.PZ.

      (Pueyo et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Pi3K68DScer\UAS.T:Disc\RFP-mCherry
      Pi3K68DUAS.mCherry
      Name Synonyms
      Secondary FlyBase IDs
        References (3)