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General Information
Symbol
Dmel\mir-315UAS.DsRed(Unk)
Species
D. melanogaster
Name
FlyBase ID
FBal0258690
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of mir-315 inserted into the 3' UTR of DsRed(Unk).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mis-expression of mir-315Scer\UAS.T:Disc\RFP-DsRed2 in the wing disc under the control of Scer\GAL4ptc-559.1 results in a dramatic double-wing pouch disk. Most animals expressing mir-315Scer\UAS.T:Disc\RFP-DsRed2 under the control of Scer\GAL4ptc-559.1 die during early pupal development, but culturing them at 18[o]C permits some to survive to pharate stages. Dissection of these animals from their pupal cases reveals transformations of scutellar tissue into ectopic wings.

Expression of mir-315Scer\UAS.T:Disc\RFP-DsRed2 under the control of Scer\GAL4Bx-MS1096 induces lethality.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Suppressor of
NOT Suppressor of
Phenotype Manifest In
Suppressed by
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of mir-315Scer\UAS.T:Disc\RFP-DsRed2 with NotumEPg31259 under the control of Scer\GAL4ptc-559.1 suppresses the lethality resulting from the expression of NotumEPg31259 alone.

Activation of NotumEPg31259 by using Scer\GAL4ptc-559.1 significantly suppresses the notum-to_wing transformation and wing pouch duplication induced by mir-315Scer\UAS.T:Disc\RFP-DsRed2.

When expressed in the presence (or absence) of co-expressed mir-315Scer\UAS.T:Disc\RFP-DsRed2 by using Scer\GAL4ptc-559.1, AxnScer\UAS.T:Avic\GFP induces embryo lethality.

Co-expression of AxnScer\UAS.T:Avic\GFP with mir-315Scer\UAS.T:Disc\RFP-DsRed2 under the control of Scer\GAL4Bx-MS1096 partially suppresses the lethality induced by mir-315Scer\UAS.T:Disc\RFP-DsRed2 expression.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
mir-315Scer\UAS.T:Disc\RFP-DsRed2
mir-315UAS.DsRed(Unk)
Name Synonyms
Secondary FlyBase IDs
    References (1)