FlyBase Allele Report: Dmel\CrebA[KK108357]

General Information

Symbol

Dmel\CrebA^KK108357

Species

D. melanogaster

Name

FlyBase ID

FBal0259663

Feature type

allele

Associated gene

Dmel\CrebA

Associated Insertion(s)

Carried in Construct

P{KK108357}

Also Known As

UAS-crebA^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK108357}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK108357

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased efficacy of long-term memory | adult stage, with Scer\GAL4^MRP-BG02822

(Hsu et al., 2025)

visible, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Phenotype Manifest In

wing, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Detailed Description

Statement

Reference

Expression of CrebA^KK108357 under the control of Scer\GAL4^VT016811 or Scer\GAL4^VT041043, in combination with a Gal80[ts] transgene to restrict expression to the 5-7 days of the adult stage immediately before, and the 24 h during, experimentation, does not significantly affect aversive olfactory long term memory in adults, compared to controls, when flies undergo spaced training.

(Wu et al., 2017)

Expression of CrebA^KK108357 under the control of Scer\GAL4^Bx-MS1096 results in male flies with severe wing size and patterning defects.

Expression of CrebA^KK108357 under the control of Scer\GAL4^Bx-MS1096 results in female flies with weak wing size and patterning defects.

(Schertel et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

CrebA^KK108357, Scer\GAL4^MRP-BG02822 has decreased efficacy of long-term memory | adult stage phenotype, non-suppressible by Rrp1^UAS.cHa, Scer\GAL4^MRP-BG02822

(Hsu et al., 2025)

Suppressor of

Statement

Reference

CrebA^KK108357, Scer\GAL4^MRP-BG02822 is a suppressor of increased efficacy of long-term memory | adult stage phenotype of Rrp1^UAS.cHa, Scer\GAL4^MRP-BG02822

(Hsu et al., 2025)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v110650

P{KK108357}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

CrebA^KK108357

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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