FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\GαoKK109018
Open Close
General Information
Symbol
Dmel\GαoKK109018
Species
D. melanogaster
Name
FlyBase ID
FBal0259763
Feature type
allele
Associated gene
Dmel\Gαo
Associated Insertion(s)
Carried in Construct
P{KK109018}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK109018}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK109018
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The number of natural synaptopods (motile filopodia-like extensions) at type II neuromuscular junctions is significantly increased compared to wild type in third instar larvae expressing G-oα47AKK109018 under the control of Scer\GAL4Tdc2.PC. The number of type II boutons at the neuromuscular junction is also increased in these larvae.

      The number of type I boutons at the neuromuscular junction is normal in third instar larvae expressing G-oα47AKK109018 under the control of Scer\GAL4Tdc2.PC.

      The number of type II boutons at the neuromuscular junction is increased compared to wild type in third instar larvae expression G-oα47AKK109018 under the control of Scer\GAL4futsch-C380.

      In contrast to wild type, type II neuromuscular junctions do not show an increase in the number of natural synaptopods in response to octopamine in third instar larvae expressing G-oα47AKK109018 under the control of Scer\GAL4Tdc2.PC.

      In contrast to wild type, larvae expressing G-oα47AKK109018 under the control of Scer\GAL4Tdc2.PC fail to respond to starvation by increasing locomotor speed.

      The number of type I boutons at the neuromuscular junction is increased compared to wild type in third instar larvae expressing G-oα47AKK109018 under the control of either Scer\GAL4futsch-C380 or Scer\GAL4BG439.

      (Koon and Budnik, 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      G-oα47AKK109018
      GαoKK109018
      Name Synonyms
      Secondary FlyBase IDs
        References (6)