FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\spzUASp.Tag:HA
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General Information
Symbol
Dmel\spzUASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0260660
Feature type
allele
Associated gene
Dmel\spz
Associated Insertion(s)
Carried in Construct
P{UASp-spz.HA}
Key Links
Transgenic product class
wild_type
(Cho et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Cho et al., 2010)
Mutagen
in vitro construct
(Cho et al., 2010)
Progenitor genotype
Carried in construct
P{UASp-spz.HA}
Cytology
Description

UASp sequences drive expression of a functional version of spz tagged at its carboxy terminus with three tandem copies of Tag:HA.

(Cho et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
spz
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4otu.T:Hsim\VP16-mediated expression of spzScer\UAS.P\T.T:Ivir\HA1 leads to the production of embryos with a ventralized cuticle phenotype.

      (Cho et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of piphs.PS increases the level of cuticle ventralization in embryos produced from Scer\GAL4otu.T:Hsim\VP16, spzScer\UAS.P\T.T:Ivir\HA1 mothers.

      (Cho et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      spzUASp.Tag:HA rescues spzunspecified

      (Cho et al., 2010)
      Comments

      Expression of spzScer\UAS.P\T.T:Ivir\HA1 in the female germline using Scer\GAL4unspecified restores lateral and/or ventral pattern elements to progeny embryos of homozygous spzunspecified females (that would otherwise have been completely dorsalized).

      (Cho et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      spzScer\UAS.P\T.T:Ivir\HA1
      spzUASp.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)