FlyBase Allele Report: Dmel\S6k[NIG.10539R]

General Information

Symbol

Dmel\S6k^NIG.10539R

Species

D. melanogaster

Name

FlyBase ID

FBal0260674

Feature type

allele

Associated gene

Dmel\S6k

Associated Insertion(s)

Carried in Construct

P{NIG.10539R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Resnik-Docampo and de Celis, 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Resnik-Docampo and de Celis, 2011)

Mutagen

in vitro construct

(Resnik-Docampo and de Celis, 2011)

Progenitor genotype

Carried in construct

P{NIG.10539R}

Cytology

Description

UASt drives expression of an RNAi construct targeting S6k.

(Resnik-Docampo and de Celis, 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-10539R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

decreased cell number, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Phenotype Manifest In

wing, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Detailed Description

Statement

Reference

Expression of S6k^NIG.10539R using Scer\GAL4^nub-AC-62 results in abnormally small wings in which cell number is decreased.

(Resnik-Docampo and de Celis, 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

S6k^NIG.10539R, Scer\GAL4^nub-AC-62 has abnormal size phenotype, enhanceable by hppy^UAS.cMa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Enhancer of

Statement

Reference

S6k^NIG.10539R, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

S6k^NIG.10539R, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell size phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

S6k^NIG.10539R, Scer\GAL4^nub-AC-62 has wing phenotype, enhanceable by hppy^UAS.cMa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Enhancer of

Statement

Reference

S6k^NIG.10539R, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of S6k^NIG.10539R and hppy^Scer\UAS.cMa using Scer\GAL4^nub-AC-62 results in a moderately synergistic phenotype of reduced wing size.

(Resnik-Docampo and de Celis, 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

10539R-2

P{NIG.10539R}2

10539R-3

P{NIG.10539R}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

S6k^NIG.10539R

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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