FB2026_02 , released June 18, 2026
Allele: Dmel\RokCA.UASp.Tag:HA
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General Information
Symbol
Dmel\RokCA.UASp.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0260793
Feature type
allele
Associated gene
Dmel\Rok
Associated Insertion(s)
Carried in Construct
P{UASp-HA-Rok.CA}
Key Links
Transgenic product class
inframe_deletion
(Simões et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Simões et al., 2010)
Mutagen
in vitro construct
(Simões et al., 2010)
Progenitor genotype
RokUASp.Tag:HA
(Simões et al., 2010)
Carried in construct
P{UASp-HA-Rok.CA}
Cytology
Description

The first 553 codons of Rok cDNA (resulting in constitutive kinase activity) and a Tag:HA tag are cloned downstream of UASp regulatory sequences.

(Simões et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Rok
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Macrophages expressing RokCA.Scer\UAS.P\T.T:Ivir\HA1 via Scer\GAL4Hml.Δ (restricted to late third instar larval stage using the Gal80ts system) show an increased number of stress fibers.

      (Lammel et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Macrophages co-expressing FhosFL.Scer\UAS.T:Avic\GFP-EGFP and RokCA.Scer\UAS.P\T.T:Ivir\HA1 via Scer\GAL4Hml.Δ (restricted to late third instar larval stage using the Gal80ts system) show complete reorganization of actin filament bundles into a star-like pattern emerging from the cell center.

      (Lammel et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RokCA.Scer\UAS.P\T.T:Ivir\HA1
      RokCA.UASp.Tag:HA
      rokCA.Scer\UAS.P\T.T:Ivir\HA1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)