FB2026_02 , released June 18, 2026
Allele: Dmel\dcoS101R
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General Information
Symbol
Dmel\dcoS101R
Species
D. melanogaster
Name
FlyBase ID
FBal0260859
Feature type
allele
Associated gene
Dmel\dco
Associated Insertion(s)
Carried in Construct
P{dco.S101R}
Key Links
Transgenic product class
missense_variant
(Dolezal et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Dolezal et al., 2010)
Mutagen
in vitro construct
(Dolezal et al., 2010)
Progenitor genotype
Carried in construct
P{dco.S101R}
Cytology
Description

A 6kb genomic fragment of dco carrying a S101R amino acid change.

(Dolezal et al., 2010)

Amino acid replacement: S101R.

(Dolezal et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
dco
Encoded product / tool
dco
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The presence of dcot.L39Q and dcot.S101R in a dcole88/Df(3R)A177der20 background results in an extended larval development period. The discs do not grow larger than normal, but the tissue seems to disintegrate in places, indicating a loss of tissue integrity.

      The presence of dcot.L39Q and dcot.S101R in a dcole88/Df(3R)A177der20 background results in a very mild dominant effect on a crossvein in the adult wing, with less than 15% penetrance.

      (Dolezal et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      dcoS101R
      dcot.S101R
      Name Synonyms
      Secondary FlyBase IDs
        References (1)