FB2026_02 , released June 18, 2026
Allele: Dmel\Mrp4EP3655
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General Information
Symbol
Dmel\Mrp4EP3655
Species
D. melanogaster
Name
FlyBase ID
FBal0261007
Feature type
allele
Associated gene
Dmel\Mrp4
Associated Insertion(s)
P{EP}Mrp4EP3655
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EP}Mrp4EP3655
    Cytology
    Description

    P{EP}Mrp4EP3655 is inserted 47 bp upstream of the Mrp4 transcription start site and directs over-expression of Mrp4 in the presence of Scer\GAL4.

    (Huang and Haddad, 2007)
    Allele components
    Component
    Use(s)
    Inserted element
    P{EP}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Flies expressing Mrp4EP3177 using Scer\GAL4da.G32 or Scer\GAL4Act.PU display a profound increase in recovery time after anoxia compared with controls.

        No pupae form when Mrp4EP3655 is expressed with Scer\GAL4da.G32 under chronic hypoxia conditions. This is in contrast to controls which show no larval developmental defects and die during late pupal stages under the same conditions.

        (Huang and Haddad, 2007)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Mrp4EP3655
        Name Synonyms
        Secondary FlyBase IDs
          References (1)