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General Information
Symbol
Dmel\numbHMS01459
Species
D. melanogaster
Name
FlyBase ID
FBal0263367
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Numb RNAi
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Newly formed secondary neuroblasts in larval brains expressing numbHMS01459 under the control of Scer\GAL4insc-Mz1407 exhibit increased nucleolar size, but no significant difference in immature secondary neuroblast numbers, as compared to wild type.

Larval optic lobe post-mitotic neuron clones expressing numbHMS01459 under the control of Scer\GAL4Act.PU include ectopic neuroblasts.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
NOT suppressed by
NOT Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of MycKK103869, but not bansponge.Scer\UAS.T:Disc\RFP, suppresses the increased nucleolar size seen in secondary neuroblasts of larval brains expressing numbHMS01459 under the control of Scer\GAL4insc-Mz1407.

Co-expression of both bansponge.Scer\UAS.T:Disc\RFP and numbHMS01459 fails to suppress the ectopic neuroblast formation and increased neuroblast numbers seen in larval brains expressing NScer\UAS.T:SV5\V5,T:Zzzz\His6 under the control of Scer\GAL4insc-Mz1407.

Co-expression of numbHMS01459 fails to suppress the increased neuroblast number seen in larval brains expressing NScer\UAS.T:SV5\V5,T:Zzzz\His6 under the control of Scer\GAL4insc-Mz1407.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
numbHMS01459
Name Synonyms
Secondary FlyBase IDs
    References (3)