FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Syt7RNAi.UAS
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General Information
Symbol
Dmel\Syt7RNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0263558
Feature type
allele
Associated gene
Dmel\Syt7
Associated Insertion(s)
Carried in Construct
P{UAS-Syt7.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Saraswati et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Saraswati et al., 2007)
Mutagen
in vitro construct
(Saraswati et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Syt7.RNAi}
Cytology
Description

UAS drives expression of a Syt7 RNAi construct encoding a ~3.2 kb genomic fragment (consisting of the first two exons and introns, including all splice donor and acceptor sites) and a reverse ~300 bp cDNA sequence (consisting of the first two exons).

(Saraswati et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Syt7
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      There are no statistical differences in evoked excitatory junctional potential amplitudes between Syt7dsRNA.Scer\UAS, Scer\GAL4elav-C155 animals and controls, even at low 0.1 mM extracellular Ca[2+] concentrations. Also, the amount of facilitation at all interpulse intervals tested was statistically the same as controls, indicating paired-pulse facilitation is unaffected.

      (Saraswati et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Scer\GAL4elav-C155/Syt7RNAi.UAS is a non-enhancer of uncoordinated phenotype of Syt1AD4/Syt1N13

      (Saraswati et al., 2007)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Syt1AD4/Syt1N13 mutants that also express Syt7dsRNA.Scer\UAS under the control of Scer\GAL4elav-C155 hatch and exhibit uncoordinated and slow movements (similar to Syt1AD4/Syt1N13 mutants alone), but then die during the first larval instar stage.

      (Saraswati et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Syt7RNAi.UAS
      Syt7dsRNA.Scer\UAS
      Syt7dsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)