FlyBase Allele Report: Scer\GAL4[Dsk.PP]

General Information

Symbol

Scer\GAL4^Dsk.PP

Species

S. cerevisiae

Name

FlyBase ID

FBal0263868

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Dsk-GAL4.P}

Also Known As

DSK-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Park et al., 2008)

Progenitor genotype

Carried in construct

P{Dsk-GAL4.P}

Cytology

Description

A 706bp fragment of Dsk upstream sequence is fused upstream of sequence encoding a GAL4 driver.

(Park et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

Dsk

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

larval Drosulfakinin neuron of pars intercerebralis

(Park et al., 2008)

wandering third instar larval stage

larval peptidergic neuron | subset

(Veenstra, 2009)

adult stage

Drosulfakinin neuron

(Hadjieconomou et al., 2020)

adult Drosulfakinin MP1 neuron

(Park et al., 2008)

adult Drosulfakinin neuron of pars intercerebralis

(Söderberg et al., 2012)

superior neuropils | restricted

(Söderberg et al., 2012)

neurosecretory cell of pars intercerebralis

(Söderberg et al., 2012)

Additional Information

Statement

Reference

Marker for

Drosulfakinin neuron

(Hadjieconomou et al., 2020)

Reflects expression of

Dsk

(Hadjieconomou et al., 2020, Park et al., 2008)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal chemosensory behavior | adult stage, with Dsk^GD6123

(Söderberg et al., 2012)

abnormal chemosensory behavior | adult stage, with Ork1^{Δ-C.UAS.EGFP}

(Söderberg et al., 2012)

abnormal chemosensory behavior | larval stage, with Dsk^GD6123

(Söderberg et al., 2012)

abnormal feeding behavior | adult stage, with Dsk^GD6123

(Söderberg et al., 2012)

abnormal feeding behavior | adult stage, with Ork1^{Δ-C.UAS.EGFP}

(Söderberg et al., 2012)

abnormal feeding behavior | larval stage, with Dsk^GD6123

(Söderberg et al., 2012)

abnormal locomotor behavior | larval stage, with Dsk^GD6123

(Söderberg et al., 2012)

abnormal sleep | adult stage, with InR^K414P.UAS

(Palermo et al., 2022)

abnormal starvation stress response | adult stage, with Dsk^GD6123

(Söderberg et al., 2012)

increased rate of feeding behavior | adult stage, with InR^K414P.UAS

(Palermo et al., 2022)

Phenotype Manifest In

Detailed Description

Statement

Reference

Inhibition (using Ork1^{Δ-C.UAS.EGFP}) of Scer\GAL4^Dsk.PP cells in adult males significantly increases feeding on undesirable food in a choice assay, compared to controls.

(Söderberg et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

DSK^Gal4

(Devineni et al., 2013)

Scer\GAL4^Dsk.PP

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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