FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\jarGCN4.Hsp83.GFP
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General Information
Symbol
Dmel\jarGCN4.Hsp83.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0264034
Feature type
allele
Associated gene
Dmel\jar
Associated Insertion(s)
Carried in Construct
P{Hsp83-jar.GCN4.GFP}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Noguchi et al., 2009)
Progenitor genotype
Carried in construct
P{Hsp83-jar.GCN4.GFP}
Cytology
Description

A Hsp83 promoter drives expression of full length jar into which the leucine zipper dimerization sequence from the Saccharomyces cerevisiae GCN4 gene has been inserted, at the end of the coiled-coil domain (between amino acids 1018 and 1019). This is designed to force protein dimer formation. The protein is also tagged with GFP.

(Noguchi et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp83
Encoded product / tool
jar
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      jarGCN4.Hsp83.GFP partially rescues jar1/Df(3R)crb87-5

      (Noguchi et al., 2009)
      Comments

      Expression of jarHsp83.T:Avic\GFP,T:Scer\GCN4 partially rescues the actin cone morphology and movement defects seen in jar1/Df(3R)crb87-5.

      Expression of jarHsp83.T:Avic\GFP,T:Scer\GCN4 partially rescues the sperm individualisation defects seen in jar1/Df(3R)crb87-5. Many sperm tails fail to individualise and in those that have, many have not completed cytoplasmic exclusion.

      Expression of jarHsp83.T:Avic\GFP,T:Scer\GCN4 partially rescues the fertility defects seen in jar1/Df(3R)crb87-5 mutants.

      Expression of jarHsp83.T:Avic\GFP,T:Scer\GCN4 partially rescues the empty seminal vesicle phenotype seen in jar1/Df(3R)crb87-5, although many seminal vesicles containing very few sperm are still present.

      (Noguchi et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      jarGCN4.Hsp83.GFP
      jarHsp83.T:Avic\GFP,T:Scer\GCN4
      Name Synonyms
      Secondary FlyBase IDs
        References (1)