FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\exUASp.EGFP
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General Information
Symbol
Dmel\exUASp.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0264319
Feature type
allele
Associated gene
Dmel\ex
Associated Insertion(s)
Carried in Construct
P{UASp-ex.eGFP}
Also Known As
UAS-ex-GFP, UAS-Ex
Key Links
Transgenic product class
wild_type
(Badouel et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Badouel et al., 2009)
Mutagen
in vitro construct
(Badouel et al., 2009)
Progenitor genotype
Carried in construct
P{UASp-ex.eGFP}
Cytology
Description

UASp regulatory sequences drive expression of full length ex tagged with EGFP.

(Badouel et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
ex
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  cancer
      modeled by Ptp61FΔ, Ras85DV12.cUa.UAS
      (Liu et al., 2022)
      ameliorates  intestinal cancer
      modeled by Ptp61FHMS00421
      (Liu et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of exScer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4nub-AC-62 results in moderate wing undergrowth phenotype as the wing area is significantly reduced compared to controls.

      (Su et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The wing undergrowth observed in flies expressing exScer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4nub-AC-62 (their wing area is significantly decreased compared to controls) is increased by co-expression of crbGD14463 (which on its own leads to wing overgrowth).

      (Su et al., 2017)

      Expression of exScer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4Act.PU suppresses the head overgrowth seen in mopsfv3 Df(3L)H99 mutant clones (generated in a minute background).

      (Gilbert et al., 2011)

      Expression of exScer\UAS.P\T.T:Avic\GFP-EGFP under the control of Scer\GAL4tub.PU largely suppresses the overgrowth phenotype seen in wtsx1 larval eye disc clones. The eye discs are no longer drastically deformed and retain a more normal shape. The pupal stage lethality is also partially rescued.

      (Badouel et al., 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      exScer\UAS.P\T.T:Avic\GFP-EGFP
      exUASp.EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (6)