FlyBase Allele Report: Dmel\CG10939[EP2037]

General Information

Symbol

Dmel\CG10939^EP2037

Species

D. melanogaster

Name

FlyBase ID

FBal0264504

Feature type

allele

Associated gene

Dmel\CG10939

Associated Insertion(s)

P{EP}CG10939^EP2037

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{EP}CG10939^EP2037

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:17,394,569..17,394,569 [+]

(Hughes et al., 2010)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(Hughes et al., 2010)

Phenotype Manifest In

wing vein | ectopic, with Scer\GAL4^Bx-MS1096

(Hughes et al., 2010)

wing vein L3, with Scer\GAL4^Bx-MS1096

(Hughes et al., 2010)

Detailed Description

Statement

Reference

Expression of Sip1^EP2037 under the control of Scer\GAL4^Bx-MS1096 results in cuticular vesicles forming along the L3 wing vein and some ectopic wing vein material.

(Hughes et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

CG10939^EP2037, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Moe^UAS.Tag:MYC, Scer\GAL4^Bx-MS1096

(Hughes et al., 2010)

CG10939^EP2037, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Moe^{T559D.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096

(Hughes et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

CG10939^EP2037, Scer\GAL4^Bx-MS1096 has wing vein phenotype, enhanceable by Moe^UAS.Tag:MYC, Scer\GAL4^Bx-MS1096

(Hughes et al., 2010)

Other

Statement

Reference

CG10939^EP2037, Moe^UAS.Tag:MYC, Scer\GAL4^Bx-MS1096 has wing blade phenotype

(Hughes et al., 2010)

CG10939^EP2037, Moe^{T559D.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing blade phenotype

(Hughes et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Moe^{Scer\UAS.T:Hsap\MYC} moderately enhances the wing vein defects caused by expression of Sip1^EP2037 under the control of Scer\GAL4^Bx-MS1096 and results in wings that are curved upwards.

Animals co-expressing Moe^{T559A.Scer\UAS.T:Hsap\MYC} and Sip1^EP2037 under the control of Scer\GAL4^Bx-MS1096 have wild-type wings.

Animals co-expressing Moe^{T559D.Scer\UAS.T:Hsap\MYC} and Sip1^EP2037 under the control of Scer\GAL4^Bx-MS1096 have wings that are dramatically reduced in size and have large blisters and cuticular vesicles.

(Hughes et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG10939^EP2037

Sip1^EP2037

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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