FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\morgue126
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General Information
Symbol
Dmel\morgue126
Species
D. melanogaster
Name
FlyBase ID
FBal0264701
Feature type
allele
Associated gene
Dmel\morgue
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schreader et al., 2010)
Progenitor genotype
P{SUPor-P}Elp3KG02386
(Schreader et al., 2010)
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a 1131bp deletion that removes part of the morgue gene (the deletion ends at Ala321).

(Schreader et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:4,443,583..4,444,713 [-]
Comment:

1131 bp deletion resulting from the imprecise excision of P{SUPor-P}Elp3KG02386, which extends from the insertion site to amino acid residue A321 of morgue. Boundaries approximate.

(Schreader et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous flies are somewhat lethargic.

      One or both of the anterior spiracles of the pupal case fail to evert and extend in 10% of homozygotes. 10.2% of eclosed homozygous adults show malformations in the tergite plates on the dorsal abdomen.

      Stage 16 mutant embryos have 1-2 additional midline glia in several, but not all, ventral nerve cord ganglia. The mutant embryos also have aberrant midline glial cytoplasmic processes that are not well separated and often extend across inter-ganglia borders.

      The average number of larval photoreceptor neurons is normal in stage 16 mutant embryos, however there is greatly increased variability in the number of neurons per cluster in the mutant embryos compared to wild type. The mutant embryos also show substantial asymmetry in the number of neurons within each of the two photoreceptor neuron clusters.

      (Schreader et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      morgue126/morgue[+] is a suppressor of visible phenotype of hidGMR.PG

      (Schreader et al., 2010)

      morgue126/morgue[+] is a suppressor of increased cell death phenotype of hidGMR.PG

      (Schreader et al., 2010)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      morgue126/morgue[+] is a suppressor of eye phenotype of hidGMR.PG

      (Schreader et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The ectopic eye death seen in flies carrying WGMR.PG is dominantly suppressed by morgue126.

      (Schreader et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      morgue126
      (Schreader et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)