FlyBase Allele Report: Dmel\Ser[UAS.cUa]

General Information

Symbol

Dmel\Ser^UAS.cUa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0265715

Feature type

allele

Associated gene

Dmel\Ser

Associated Insertion(s)

Carried in Construct

P{UAS-Ser.U}

Also Known As

UAS-Ser

Key Links

Allele class

Mutagen

in vitro construct - regulatory fusion

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Griffiths et al., 2007)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{UAS-Ser.U}

Cytology

Nature of the lesion

Statement

Reference

UAS regulatory sequences drive expression of Ser.

(Griffiths et al., 2007)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Ser

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^htl.POS

(Griffiths et al., 2007)

visible, with Scer\GAL4^Ser.PGF

(Fleming et al., 2013)

visible | adult stage, with Scer\GAL4^dpp.PU

(Imai et al., 2015)

Phenotype Manifest In

interface glial cell, with Scer\GAL4^htl.POS

(Griffiths et al., 2007)

wing margin, with Scer\GAL4^Ser.PGF

(Fleming et al., 2013)

wing margin bristle | increased number, with Scer\GAL4^dpp.PU

(Imai et al., 2015)

wing vein, with Scer\GAL4^Ser.PGF

(Fleming et al., 2013)

Detailed Description

Statement

Reference

Adult flies expressing Ser^Scer\UAS.cUa under the control of Scer\GAL4^dpp.PU have ectopic bristles at the adult wing margin.

(Imai et al., 2015)

Expression of Ser^Scer\UAS.cUa under the control of Scer\GAL4^Ser.PGF results in a notched wing margin and wing vein deltas.

(Fleming et al., 2013)

Expression of Ser^Scer\UAS.cUa under the control of Scer\GAL4^htl.POS results in the loss of almost all longitudinal glia in the embryo.

(Griffiths et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^dpp.PU, Ser^UAS.cUa has visible | adult stage phenotype, non-enhanceable by Neurl4^EY12221, Scer\GAL4^dpp.PU

(Imai et al., 2015)

Scer\GAL4^dpp.PU, Ser^UAS.cUa has visible | adult stage phenotype, non-enhanceable by HERC2^G17171, Scer\GAL4^dpp.PU

(Imai et al., 2015)

Scer\GAL4^dpp.PU, Ser^UAS.cUa has visible | adult stage phenotype, non-enhanceable by Hsap\LRRK2^UAS.cVa, Scer\GAL4^dpp.PU

(Imai et al., 2015)

Suppressor of

Statement

Reference

Scer\GAL4^bbg-C96/Ser^UAS.cUa is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^bbg-C96, Yif1^GD302

(Kandasamy et al., 2021)

Scer\GAL4^bbg-C96/Ser^UAS.cUa is a suppressor | partially of decreased size | adult stage phenotype of Scer\GAL4^bbg-C96, Yif1^GD302

(Kandasamy et al., 2021)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^dpp.PU, Ser^UAS.cUa has wing margin bristle | increased number phenotype, non-enhanceable by Neurl4^EY12221, Scer\GAL4^dpp.PU

(Imai et al., 2015)

Scer\GAL4^dpp.PU, Ser^UAS.cUa has wing margin bristle | increased number phenotype, non-enhanceable by HERC2^G17171, Scer\GAL4^dpp.PU

(Imai et al., 2015)

Scer\GAL4^dpp.PU, Ser^UAS.cUa has wing margin bristle | increased number phenotype, non-enhanceable by Hsap\LRRK2^UAS.cVa, Scer\GAL4^dpp.PU

(Imai et al., 2015)

Suppressor of

Statement

Reference

Scer\GAL4^bbg-C96/Ser^UAS.cUa is a suppressor | partially of wing margin phenotype of Scer\GAL4^bbg-C96, Yif1^GD302

(Kandasamy et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

The ectopic wing margin bristle phenotype characteristic for adult flies expressing Ser^Scer\UAS.cUa under the control of Scer\GAL4^dpp.PU is not significantly modified by co-expression of either Neurl4^EY12221 or HERC2^G17171.

(Imai et al., 2015)

Xenogenetic Interactions

Statement

Reference

(Imai et al., 2015)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ser^Scer\UAS.cUa

Ser^UAS.cUa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (7)

Report Sections

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