FB2026_02 , released June 18, 2026
Allele: Dmel\Sema2bTag:HA
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General Information
Symbol
Dmel\Sema2bTag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0266712
Feature type
allele
Associated gene
Dmel\Sema2b
Associated Insertion(s)
Carried in Construct
PBac{Sema2b.W}
Also Known As
BAC:Sema-2b
Key Links
Transgenic product class
wild_type
(Wu et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wu et al., 2011)
Mutagen
in vitro construct
(Kolodkin, 2016.7.28, Wu et al., 2011)
Progenitor genotype
Carried in construct
PBac{Sema2b.W}
Cytology
Description

Encodes Sema2b tagged with 3 copies of Tag:HA.

(Kolodkin, 2016.7.28)

Fragment containing the Sema-2b gene. The sequence encoding the Menl-1 and Menl-2 genes (found in an intron of Sema-2b) has been removed to ensure coverage of only Sema-2b.

(Wu et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Sema2b
Encoded product / tool
Sema2b
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Sema2bT:Ivir\HA1 rescues the ISNb and SNa axon pathfinding defects observed in homozygous Df(2R)Sema2b-C4 mutant embryos.

      (Roh et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Sema2bTag:HA rescues Df(2R)Sema2b-C4

      (Wu et al., 2011)
      Comments

      Sema-2b+tWa rescues the longitudinal connective defects of Df(2R)Sema-2b-C4 mutant embryos, including the defects seen in the intermediate Fas2-positive longitudinal tracts.

      (Wu et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Sema-2b+tWa
      Sema-2bT:Ivir\HA1
      Sema2bT:Ivir\HA1
      Sema2bTag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (4)