FB2026_02 , released June 18, 2026
Allele: Dmel\shgR758
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General Information
Symbol
Dmel\shgR758
Species
D. melanogaster
Name
FlyBase ID
FBal0267132
Feature type
allele
Associated gene
Dmel\shg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele

Mutagen
Nature of the Allele
Allele class

hypomorphic allele

(Taniguchi et al., 2011)
Mutagen
ethyl methanesulfonate
(Taniguchi et al., 2011)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous and shgR758/shgR69 embryos show defects in the left-right asymmetry of the hindgut: left-right inversion and bilateralism phenotypes are seen at stage 14 in the mutant embryos.

      (Taniguchi et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      shgR758 is rescued by shgUAS.sgGFP/Scer\GAL4VP16.mat.αTub67C

      (Taniguchi et al., 2011)

      shgR758 is rescued by shgUAS.sgGFP/Scer\GAL4455.2

      (Taniguchi et al., 2011)
      Not rescued by

      shgR758 is not rescued by shgUAS.sgGFP/Scer\GAL448Y

      (Taniguchi et al., 2011)

      shgR758 is not rescued by Scer\GAL4how-24B/shgUAS.sgGFP

      (Taniguchi et al., 2011)
      Comments

      The defects in the left-right asymmetry of the hindgut which are seen in homozygous shgR758 embryos are rescued by expression of shgScer\UAS.T:Avic\GFP-rs under the control of either Scer\GAL4mat.αTub67C.T:Hsim\VP16 or Scer\GAL4455.2, but are not rescued by expression of shgScer\UAS.T:Avic\GFP-rs under the control of either Scer\GAL448Y or Scer\GAL4how-24B.

      (Taniguchi et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      shgR758
      (Taniguchi et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)