FlyBase Allele Report: Dmel\Nos[UAS.cMa]

General Information

Symbol

Dmel\Nos^UAS.cMa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of McGettigan

FlyBase ID

FBal0267693

Feature type

allele

Associated gene

Dmel\Nos

Associated Insertion(s)

Carried in Construct

P{UAS-Nos.M}

Key Links

Transgenic product class

wild_type

(McGettigan et al., 2005)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(McGettigan et al., 2005)

Mutagen

in vitro construct

(McGettigan et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-Nos.M}

Cytology

Description

UAS regulatory sequences drive expression of Nos.

(McGettigan et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Nos

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during P-stage, with Nos^Δ15, Scer\GAL4^ey-OK107

(Rabinovich et al., 2016)

viable, with Scer\GAL4^ey-OK107

(Rabinovich et al., 2016)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Nos^Scer\UAS.cMa under the control of Scer\GAL4^ey-OK107 does not significantly affect axon regrowth in the mushroom body gamma-lobe.

Expression of Nos^Scer\UAS.cMa under the control of Scer\GAL4^ey-OK107 in a Nos^Δ15/Nos^Δ15 background results in early pupal lethality.

(Rabinovich et al., 2016)

Flies expressing Nos^Scer\UAS.cMa under the control of Scer\GAL4^c42 show increased survival after infection with E. coli compared to either control Nos^Scer\UAS.cMa or Scer\GAL4^c42 line.

(McGettigan et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Nos^UAS.cMa, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, foxo^UAS.cPa

(Kanao et al., 2012)

Phenotype Manifest In

Enhancer of

Statement

Reference

Nos^UAS.cMa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, foxo^UAS.cPa

(Kanao et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Cam^Scer\UAS.cWa and Nos^Scer\UAS.cMa under the control of Scer\GAL4^ey-OK107 does not significantly affect axon regrowth in the mushroom body gamma-lobe.

(Rabinovich et al., 2016)

Co-expression of Nos^Scer\UAS.cMa enhances the eye defects caused by expression of foxo^Scer\UAS.cPa under the control of Scer\GAL4^GMR.PF.

(Kanao et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Nos^Scer\UAS.cMa

Nos^UAS.cMa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of McGettigan

Secondary FlyBase IDs

References (3)

Report Sections

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