FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gk2UAS.Ex
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General Information
Symbol
Dmel\Gk2UAS.Ex
Species
D. melanogaster
Name
FlyBase ID
FBal0268042
Feature type
allele
Associated gene
Dmel\Gk2
Associated Insertion(s)
Carried in Construct
P{UAS-Gk2.Ex}
Also Known As
dGK-OE
Key Links
Transgenic product class
wild_type
(Wightman et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wightman et al., 2012)
Mutagen
in vitro construct
(Wightman et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Gk2.Ex}
Cytology
Description

UAS regulatory sequences drive expression of the Gk2 coding region.

(Wightman et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Gk2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Gk2UAS.Ex, Scer\GAL4c564 is a suppressor of chemical sensitive phenotype of Gk1RNAi.UAS, Scer\GAL4c564

      (Wightman et al., 2012)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of GkScer\UAS.Ex rescues the reduced survival on a glycerol only food source of flies expressing GykdsRNA.Scer\UAS under the control of Scer\GAL4c564.

      (Wightman et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Co-expression of Gk2Scer\UAS.Ex significantly reduces the larval lethality seen with expression of Gk2dsRNA.Scer\UAS-let driven by Scer\GAL4c564.

      (Wightman et al., 2013)

      Co-expression of GkScer\UAS.Ex rescues the reduced survival on a glycerol only food source of flies expressing GkdsRNA.Scer\UAS under the control of Scer\GAL4c564.

      (Wightman et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gk2Scer\UAS.Ex
      Gk2UAS.Ex
      GkScer\UAS.Ex
      Name Synonyms
      Secondary FlyBase IDs
        References (2)