FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\BruceBIR.UAS
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General Information
Symbol
Dmel\BruceBIR.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0268095
Feature type
allele
Associated gene
Dmel\Bruce
Associated Insertion(s)
Carried in Construct
P{UAS-Bruce.BIR}
Key Links
Transgenic product class
inframe_deletion
(Domingues and Ryoo, 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Domingues and Ryoo, 2012)
Mutagen
in vitro construct
(Domingues and Ryoo, 2012)
Progenitor genotype
Carried in construct
P{UAS-Bruce.BIR}
Cytology
Description

Residues 1-531 of Bruce, including the BIR domain, are cloned downstream of UAS regulatory sequences.

(Domingues and Ryoo, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Bruce
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      BruceBIR.UAS/Scer\GAL4GMR.PU is a suppressor of eye phenotype of hidGMR.PG

      (Domingues and Ryoo, 2012)

      BruceBIR.UAS/Scer\GAL4GMR.PU is a suppressor | partially of eye phenotype of rprGMR.PD

      (Domingues and Ryoo, 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of BruceBIR.Scer\UAS under the control of Scer\GAL4GMR.PF moderately suppresses the partial eye ablation seen in rprGMR.PD eyes.

      Expression of BruceBIR.Scer\UAS in the developing eye under the control of Scer\GAL4GMR.PF weakly suppresses the small eye phenotype seen in WGMR.PG mutants.

      (Domingues and Ryoo, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      BruceBIR.Scer\UAS
      BruceBIR.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)