A Dcp-1Prev1; IceΔ1 double mutant background fails to abolish the ability of Icefl.5'3'UTR mutants to induce cell death, although induction is at a reduced rate compared to in a IceΔ1 single mutant background.
The presence of the Icefl.5'3'UTR construct restores cell death after irradiation in IceΔ1 mutants.