FB2026_03 , released September 17, 2026
Allele: Dmel\slC-SH2
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General Information
Symbol
Dmel\slC-SH2
Species
D. melanogaster
Name
FlyBase ID
FBal0268607
Feature type
allele
Associated gene
Dmel\sl
Associated Insertion(s)
Carried in Construct
P{sl.C-SH2}
Key Links
Transgenic product class
missense_variant
(Murillo-Maldonado et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Murillo-Maldonado et al., 2011)
Mutagen
in vitro construct
(Murillo-Maldonado et al., 2011)
Progenitor genotype
Carried in construct
P{sl.C-SH2}
Cytology
Description

A 10kb genomic fragment containing a mutant form of the sl transcription unit in which the arginine at amino acid 726 has been replaced by alanine.

(Murillo-Maldonado et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
sl
Encoded product / tool
sl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      slC-SH2 rescues sl2

      (Murillo-Maldonado et al., 2011)
      Comments

      Expression of slC-SH2 rescues the wing size defects, ectopic veins and extra R7 photoreceptor phenotypes seen in sl2 mutants.

      (Murillo-Maldonado et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      slC-SH2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)