FlyBase Allele Report: Dmel\FASN1[NIG.3523R]

General Information

Symbol

Dmel\FASN1^NIG.3523R

Species

D. melanogaster

Name

FlyBase ID

FBal0268924

Feature type

allele

Associated gene

Dmel\FASN1

Associated Insertion(s)

Carried in Construct

P{NIG.3523R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Friedman et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Friedman et al., 2011)

Mutagen

in vitro construct

(Friedman et al., 2011)

Progenitor genotype

Carried in construct

P{NIG.3523R}

Cytology

Description

UASt regulatory sequences drive expression of a FASN1 RNAi construct.

(Friedman et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-3523R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Scer\GAL4^sal.BO

(Parvy et al., 2012)

visible, with Scer\GAL4^Bx-MS1096

(Friedman et al., 2011)

Phenotype Manifest In

brain | larval stage, with Scer\GAL4^repo

(Dong et al., 2021)

lipid droplet | larval stage, with Scer\GAL4^repo

(Dong et al., 2021)

wing, with Scer\GAL4^Bx-MS1096

(Friedman et al., 2011)

Detailed Description

Statement

Reference

Larvae expressing FASN1^NIG.3523R under the control of Scer\GAL4^repo show decreased lipid droplets in the brain lobes.

(Dong et al., 2021)

Expression of CG3523^NIG.3523R under the control of Scer\GAL4^Bx-MS1096 results in slight curling of the wing.

(Friedman et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

FASN1^NIG.3523R, Scer\GAL4^NP2222 is a suppressor of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^NP2222, hh^{N.UAS.cHa.EGFP}

(Dong et al., 2021)

FASN1^NIG.3523R, Scer\GAL4^NP2222 is a suppressor of decreased occurrence of cell division | larval stage phenotype of Scer\GAL4^NP2222, htl^λ.UAS

(Dong et al., 2021)

Phenotype Manifest In

Suppressor of

Statement

Reference

FASN1^NIG.3523R, Scer\GAL4^NP2222 is a suppressor of neuroblast | larval stage phenotype of Scer\GAL4^NP2222, hh^{N.UAS.cHa.EGFP}

(Dong et al., 2021)

FASN1^NIG.3523R, Scer\GAL4^NP2222 is a suppressor | partially of neuroblast | larval stage phenotype of Scer\GAL4^NP2222, htl^λ.UAS

(Dong et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

3523R-2

P{NIG.3523R}2

3523R-6

P{NIG.3523R}6

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG3523^NIG.3523R

FASN1^NIG.3523R

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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