FlyBase Allele Report: Dmel\Nsun2[UAS.cAa]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Nsun2^UAS.cAa

General Information

Symbol

Dmel\Nsun2^UAS.cAa

Species

D. melanogaster

Name

FlyBase ID

FBal0268996

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Transgenic product class

(Abbasi-Moheb et al., 2012)

(Abbasi-Moheb et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Abbasi-Moheb et al., 2012)

(Abbasi-Moheb et al., 2012)

Mutagen

in vitro construct

(Abbasi-Moheb et al., 2012)

Progenitor genotype

Carried in construct

Cytology

Description

UASt drives expression of a Nsun2 cDNA.

(Abbasi-Moheb et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates tauopathy

modeled by Hsap\MAPT^UAS.2N4R.cSa

(Kim et al., 2023)

ameliorates Alzheimer's disease 1

modeled by Hsap\APP^2xAPP.SP.UAS

(Kim et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Nsun2^UAS.cAa, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Hsap\MAPT^UAS.2N4R.cSa, Scer\GAL4^GMR.PU

(Kim et al., 2023)

Nsun2^UAS.cAa, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.PU

(Kim et al., 2023)

Phenotype Manifest In

Suppressor of

Statement

Reference

Nsun2^UAS.cAa, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Hsap\MAPT^UAS.2N4R.cSa, Scer\GAL4^GMR.PU

(Kim et al., 2023)

Nsun2^UAS.cAa, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Hsap\APP^2xAPP.SP.UAS, Scer\GAL4^GMR.PU

(Kim et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Nsun2^UAS.cAa/Scer\GAL4^elav.PLu rescues Nsun2^ex1

(Abbasi-Moheb et al., 2012)

Comments

Scer\GAL4^elav.PLu-mediated expression of Nsun2^Scer\UAS.cAa fully rescues the short-term memory phenotype of Nsun2^ex1 mutants.

(Abbasi-Moheb et al., 2012)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Nsun2^Scer\UAS.cAa

Nsun2^UAS.cAa

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections