FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ack10b
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General Information
Symbol
Dmel\Ack10b
Species
D. melanogaster
Name
FlyBase ID
FBal0269976
Feature type
allele
Associated gene
Dmel\Ack
Associated Insertion(s)
P{?SUPor-P}Ack10b
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Zahedi et al., 2008)
Mutagen
P-element activity
(Zahedi et al., 2008)
Progenitor genotype
P{SUPor-P}KG00869
(Zahedi et al., 2008)
Associated Insertion(s)
P{?SUPor-P}Ack10b
Cytology
Description

Imprecise excision of the progenitor insertion, resulting in a deletion that removes part of Ack. Some P-element sequences remain.

(Zahedi et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous Ack10b flies are viable and without obvious growth defects.

      (Hu et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Ack10b/Ack10b is a suppressor of visible phenotype of tkvTAJ3

      (Zahedi et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Ack10b/Ack10b is a non-suppressor of visible | somatic clone | adult stage phenotype of exe1

      (Hu et al., 2016)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Ack10b/Ack10b is a suppressor of wing vein | ectopic phenotype of tkvTAJ3

      (Zahedi et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Ack10b/Ack10b is a non-suppressor of eye | somatic clone | adult stage phenotype of exe1

      (Hu et al., 2016)

      Ack10b/Ack10b is a non-suppressor of antenna | somatic clone | adult stage phenotype of exe1

      (Hu et al., 2016)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The overgrowth phenotype observed in adult eye and antennae containing exe1 homozygous mutant somatic clones (induced by the eyFLP method) is not changed when the clones are induced in Ack10b/Ack10b mutant background.

      (Hu et al., 2016)

      tkv7/+ ; Ack10b/Ack10b embryos show dorsal closure defects at a relatively low frequency, but which is significantly higher than the frequency seen in either tkv7/+ or Ack10b/Ack10b single mutant embryos.

      Ack-likec02472 Ack10b embryos often fail to secrete cuticle. Those that do sometimes have dorsal defects in the cuticle.

      Embryos expressing Ack-likeNIG.3969R under the control of Scer\GAL4c381 in an Ack10b background often fail to secrete cuticle. Those that do sometimes have dorsal defects in the cuticle.

      The ectopic wing vein phenotype seen in tkvTAJ3 flies is significantly suppressed by Ack10b/Ack10b.

      (Zahedi et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ack10b
      (Hu et al., 2016)
      DACK10b
      (Zahedi et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)