Gene model reviewed during 5.43
Gene model reviewed during 5.45
Gene model reviewed during 5.56
There is only one protein coding transcript and one polypeptide associated with this gene
Interacts with yki and ex (PubMed:27462444). Interacts with drk (PubMed:22615583). Likely to be a member of an axonal guidance receptor complex that includes SH3PX1, dock and Dscam (PubMed:11773052). Interacts (via N-terminus) with dock (PubMed:23562806, PubMed:11773052). Interacts with SH3PX1 (via SH3 domain) (PubMed:11773052).
The SAM, Protein kinase and SH3 domains are required for sperm formation.
The SAM and SH3 domains are required for localization to clathrin-coated vesicles in spermatocytes.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ack using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ack in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
When dsRNA constructs are made and transiently transfected into S2 cells in RNAi experiments, an increase in the proportion of S phase cells and an increase in the proportion of G2/M phase cells are seen.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.