FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hnbp
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General Information
Symbol
Dmel\Hnbp
Species
D. melanogaster
Name
FlyBase ID
FBal0270023
Feature type
allele
Associated gene
Dmel\Hn
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Wang et al., 2008)
Progenitor genotype
Cytology
Description

45bp insertion in the second exon of Hn. This is predicted to result in a transcript that encodes an additional 15 amino acid residues compared to wild type.

(Wang et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
insertion
3L:7,762,105..7,762,106 [+]
Comment:

A 45 bp insertion is present between amino acid R191 and N192 of Hn-RA, which leads to an insertion of 15 amino acids relative to the wild type sequence.

(Wang et al., 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes and Hnbp/Hnr3 flies have purple eyes.

      (Wang et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Hnr3

      (Wang et al., 2008)
      Rescued by

      Hnbp is rescued by HnUASp.cWa/Scer\GAL4GMR.PU

      (Wang et al., 2008)
      Comments

      Expression of HnScer\UAS.P\T.cWa under the control of Scer\GAL4GMR.PU rescues the eye colour defect seen in Hnbp homozygotes.

      (Wang et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hnbp
      (Wang et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)