FlyBase Allele Report: Dmel\Sumo[ex77]

General Information

Symbol

Dmel\Sumo^ex77

Species

D. melanogaster

Name

FlyBase ID

FBal0270277

Feature type

allele

Associated gene

Dmel\Sumo

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Berdnik et al., 2012)

Progenitor genotype

Sumo^SH0182

(Berdnik et al., 2012)

Cytology

Description

Imprecise excision of P{lacW}smt3^SH0182 (found 10bp upstream of the smt3 transcriptional start site) generates a ~1200bp deletion that removes the entire smt3 open reading frame.

(Berdnik et al., 2012)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2L:6,966,403..6,967,603 [-]

Comment:

Approximate boundaries of a ~1.2 kb deletion resulting from the imprecise excision of P{lacW}Sumo^SH0182.

(Berdnik et al., 2012)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Berdnik et al., 2012)

lethal

(Berdnik et al., 2012)

lethal | somatic clone

(Berdnik et al., 2012)

Phenotype Manifest In

adult antennal lobe projection neuron DL1 adPN

(Berdnik et al., 2012)

antennal lobe glomerulus DL1

(Berdnik et al., 2012)

dendrite

(Berdnik et al., 2012)

Detailed Description

Statement

Reference

Those smt3^ex77 somatic clones that survive till adulthood exhibit extensive dendrite mistargeting.

(Berdnik et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Sumo^ex77/smt3[+] is a suppressor of abnormal neuroanatomy | somatic clone phenotype of velo^LL05209

(Berdnik et al., 2012)

Phenotype Manifest In

Suppressor of

Statement

Reference

Sumo^ex77/smt3[+] is a suppressor of adult antennal lobe projection neuron DL1 adPN | somatic clone phenotype of velo^LL05209

(Berdnik et al., 2012)

Sumo^ex77/smt3[+] is a suppressor of antennal lobe glomerulus DL1 | somatic clone phenotype of velo^LL05209

(Berdnik et al., 2012)

Sumo^ex77/smt3[+] is a suppressor of dendrite | somatic clone phenotype of velo^LL05209

(Berdnik et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

A smt3^ex77 heterozygous background suppress the dendritic mistargeting seen in velo^LL05209 mutant DL1 projection neurons.

(Berdnik et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

44377

y¹ w^*; Sumo^ex77 P{neoFRT}40A P{FRT(w^hs)}G13 cn¹ bw¹/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Sumo^ex77

smt3^ex77

(Berdnik et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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