FlyBase Allele Report: Dmel\Usp5[NIG.12082R]

General Information

Symbol

Dmel\Usp5^NIG.12082R

Species

D. melanogaster

Name

FlyBase ID

FBal0271101

Feature type

allele

Associated gene

Dmel\Usp5

Associated Insertion(s)

Carried in Construct

P{NIG.12082R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.12082R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-12082R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage, with Scer\GAL4^da.PU

(Kovacs et al., 2015)

majority die during pupal stage, with Scer\GAL4^da.PU

(Kovacs et al., 2015)

some die during third instar larval stage, with Scer\GAL4^da.PU

(Kovacs et al., 2015)

visible, with Scer\GAL4^bbg-C96

(Zhang et al., 2012)

visible, with Scer\GAL4^dpp.PU

(Zhang et al., 2012)

Phenotype Manifest In

scutellar bristle, with Scer\GAL4^dpp.PU

(Zhang et al., 2012)

wing, with Scer\GAL4^bbg-C96

(Zhang et al., 2012)

wing margin bristle, with Scer\GAL4^bbg-C96

(Zhang et al., 2012)

Detailed Description

Statement

Reference

Expression of CG12082^NIG.12082R under the control of Scer\GAL4^bbg-C96 results in wrinkled wings and loss of wing margin bristles.

Expression of CG12082^NIG.12082R under the control of Scer\GAL4^dpp.PU results in flies with less scutellar bristles than normal.

(Zhang et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-enhancer of visible | adult stage phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-enhancer of abnormal eye color phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-enhancer of visible | adult stage phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-enhancer of abnormal eye color phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

NOT Suppressor of

Statement

Reference

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-suppressor of visible | adult stage phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-suppressor of abnormal eye color phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-suppressor of visible | adult stage phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-suppressor of abnormal eye color phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-enhancer of eye phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-enhancer of eye phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

NOT Suppressor of

Statement

Reference

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-suppressor of eye phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp5^NIG.12082R, Scer\GAL4^GMR.PFa is a non-suppressor of eye phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The photoreceptor depigmentation phenotype characteristic for adult flies expressing either Dronc^UAS.cSa or Dronc^{S130A.UAS.cSa} under the control of Scer\GAL4^GMR.PFa is not significantly modified by the co-expression of Usp5^NIG.12082R.

(Sinenko, 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

NIG-Fly

12082R-2

P{NIG.12082R}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG12082^NIG.12082R

Usp5^NIG.12082R

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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