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General Information
Symbol
Dmel\DroncUAS.cSa
Species
D. melanogaster
Name
FlyBase ID
FBal0295941
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Dronc
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of wild-type Dronc. The coding region is not tagged.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of DroncUAS.cSa under the control of Scer\GAL4GMR.PFa results in a high proportion of depigmented eye photoreceptors in the adult eye.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

DroncUAS.cSa, Scer\GAL4GMR.PFa has visible | adult stage phenotype, enhanceable by Diap1[+]/Diap14

DroncUAS.cSa, Scer\GAL4GMR.PFa has abnormal eye color phenotype, enhanceable by Diap1[+]/Diap14

NOT Enhanced by
Statement
Reference
Suppressed by
NOT suppressed by
Statement
Reference
Phenotype Manifest In
Enhanced by
NOT Enhanced by
Statement
Reference
Suppressed by
NOT suppressed by
Statement
Reference
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The photoreceptor depigmentation phenotype characteristic for adult flies expressing DroncUAS.cSa under the control of Scer\GAL4GMR.PFa is fully suppressed by co-expression of any of the following: Usp15-31GD10077, Usp15-31KK101035, DarkKK104215 and Diap1Scer\UAS.cHa or by combination with Usp15-31KG04149. Co-expression of Usp2NIG.14619R does not suppress the depigmentation phenotype and also leads to rough eye phenotype while combination with a single copy of Diap14 strongly exacerbates the depigmentation. No effect on the DroncUAS.cSa-induced phenotype is observed upon co-expression of any of the following: Usp20-33KK104810, Usp20-33GD13944, Usp39NIG.7288R, Usp12-46KK108313, CYLDKK109096, CYLDNIG.5603R, Usp14KK102888, Usp16-45NIG.4165R, CG4968GD11489, DUBAIGD14040, CG4751GD11417, fafNIG.1945R, Usp5[GD6741] or Usp5NIG.12082R; co-expression of any of the following: Usp8KK100733, scnyKK102113, scnyGD2319, Usp7KK100635, Usp1KK106492 results in some enhancement of the eye defects.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
DroncScer\UAS.cSa
DroncUAS.cSa
NcScer\UAS.cSa
Name Synonyms
Secondary FlyBase IDs
    References (4)