FlyBase Allele Report: Dmel\Usp20-33[GD13944]

General Information

Symbol

Dmel\Usp20-33^GD13944

Species

D. melanogaster

Name

FlyBase ID

FBal0205894

Feature type

allele

Associated gene

Dmel\Usp20-33

Associated Insertion(s)

Carried in Construct

P{GD13944}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD13944}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD13944

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage, with Scer\GAL4^elav.PU

(Tsou et al., 2012)

short lived, with Scer\GAL4^sqh.PW

(Tsou et al., 2012)

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^pnr-MD237

(Mummery-Widmer et al., 2009)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

Scer\GAL4^sqh.PW, CG8494^GD13944 flies are dead by 40 days.

Scer\GAL4^elav.PU, CG8494^GD13944 adults are slower than controls.

(Tsou et al., 2012)

Expression of CG8494^GD13944 under the control of Scer\GAL4^bbg-C96 does not result in a wing phenotype.

Expression of CG8494^GD13944 under the control of Scer\GAL4^dpp.PU does not result in a bristle phenotype.

(Zhang et al., 2012)

Adults expressing Usp20-33^GD13944 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

13944

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-enhancer of visible | adult stage phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-enhancer of abnormal eye color phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-enhancer of visible | adult stage phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-enhancer of abnormal eye color phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

NOT Suppressor of

Statement

Reference

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-suppressor of visible | adult stage phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-suppressor of abnormal eye color phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-suppressor of visible | adult stage phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-suppressor of abnormal eye color phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-enhancer of eye phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-enhancer of eye phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

NOT Suppressor of

Statement

Reference

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-suppressor of eye phenotype of Dronc^UAS.cSa, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Usp20-33^GD13944, Scer\GAL4^GMR.PFa is a non-suppressor of eye phenotype of Dronc^{S130A.UAS.cSa}, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The photoreceptor depigmentation phenotype characteristic for adult flies expressing either Dronc^UAS.cSa or Dronc^{S130A.UAS.cSa} under the control of Scer\GAL4^GMR.PFa is not significantly modified by the co-expression of Usp20-33^GD13944.

(Sinenko, 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v42609

w¹¹¹⁸; P{GD13944}v42609

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 1 )

Linkouts

Bristle Screen Database (Knoblich Lab) - A database for RNAi phenotypes in bristle and notum development

13944

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG8494^GD13944

Usp20-33^GD13944

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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