FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Usp7KK100635
Open Close
General Information
Symbol
Dmel\Usp7KK100635
Species
D. melanogaster
Name
FlyBase ID
FBal0258787
Feature type
allele
Associated gene
Dmel\Usp7
Associated Insertion(s)
Carried in Construct
P{KK100635}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK100635}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK100635
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4elav.PU, Usp7KK100635 flies dies as pharates or soon after eclosion. Expression of Usp7KK100635 using a weaker Scer\GAL4elav.PU gives no phenotype.

      Expression of Usp7KK100635 using Scer\GAL4elav.PU results in a progressive drooping wing phenotype.

      (Tsou et al., 2012)

      Expression of Usp7KK100635 under the control of Scer\GAL4bbg-C96 does not result in a wing phenotype.

      (Zhang et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Usp7KK100635, Scer\GAL4GMR.PFa is an enhancer of eye phenotype of DroncUAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)
      NOT Enhancer of
      Statement
      Reference

      Usp7KK100635, Scer\GAL4GMR.PFa is a non-enhancer of eye phenotype of DroncS130A.UAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The photoreceptor depigmentation phenotype characteristic for adult flies expressing DroncUAS.cSa under the control of Scer\GAL4GMR.PFa is somewhat enhanced by the co-expression of Usp7KK100635, whereas no modification of the depigmentation induced by DroncS130A.UAS.cSa expression is observed.

      (Sinenko, 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Usp7KK100635
      Name Synonyms
      Secondary FlyBase IDs
        References (8)