FlyBase Allele Report: Dmel\Mterf4[NIG.15390R]

General Information

Symbol

Dmel\Mterf4^NIG.15390R

Species

D. melanogaster

Name

FlyBase ID

FBal0272187

Feature type

allele

Associated gene

Dmel\Mterf4

Associated Insertion(s)

Carried in Construct

P{NIG.15390R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.15390R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-15390R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased rate of adult locomotory behavior, with Scer\GAL4^Mef2.PR

(Shan et al., 2024)

increased mortality, with Scer\GAL4^Mef2.PR

(Shan et al., 2024)

short lived, with Scer\GAL4^Mef2.PR

(Shan et al., 2024)

visible | adult stage, with Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Phenotype Manifest In

mitochondrion, with Scer\GAL4^Mef2.PR

(Shan et al., 2024)

wing, with Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, enhanceable by Rel^{UAS.cSa.Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Suppressed by

Statement

Reference

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible by mtSSB^NIG.4337R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible by mtDNA-helicase^KK102418, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible by MED8^KK107827, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible by Tfb4^KK107429, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible by PolG2^GD4188, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has decreased rate of adult locomotory behavior phenotype, suppressible by MED8^KK107827, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has decreased rate of adult locomotory behavior phenotype, suppressible by PolG2^GD4188, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has decreased rate of adult locomotory behavior phenotype, suppressible by mtSSB^NIG.4337R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has decreased rate of adult locomotory behavior phenotype, suppressible by Tfb4^KK107429, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has decreased rate of adult locomotory behavior phenotype, suppressible by mtDNA-helicase^KK102418, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has short lived phenotype, suppressible by MED8^KK107827, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has short lived phenotype, suppressible by PolG2^GD4188, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has short lived phenotype, suppressible by Tfb4^KK107429, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has short lived phenotype, suppressible by mtDNA-helicase^KK102418, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has short lived phenotype, suppressible by mtSSB^NIG.4337R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, suppressible by MED8^KK107827, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, suppressible by mtDNA-helicase^KK102418, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, suppressible by PolG2^GD4188, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, suppressible by Tfb4^KK107429, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, suppressible by mtSSB^NIG.4337R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by mtSSB^{Δ1-47.Δ85-91.UAS.Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by PolG2^{Δ1-20.G31E.UAS.Tag:TM(rTomm20),Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by mtDNA-helicase^{Δ1-33.A442P.UAS.Tag:TM(rTomm20),Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by cGlr1^GD7883, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by Sting^NIG.1667R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by Dredd^NIG.7486R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by Rel^{Δ152-334.UAS.Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by Rel^HM05154, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by Dref^NIG.5838R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible | partially by PolrMT^HMS01474, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype, suppressible by Hsap\MTERF4^UAS.Tag:HA, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

NOT suppressed by

Statement

Reference

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by park^KK107919, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by Pink1^KK101205, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by SH3PX1^KK100618, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by sesB^KK108773, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by Phb1^NIG.10691R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by Debcl^GD1637, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by porin^KK107645, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has increased mortality phenotype, non-suppressible by Buffy^JF03287, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Other

Statement

Reference

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtSSB^NIG.4337R, mtSSB^UAS.Tag:HA has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, PolG2^{Δ1-20.UAS.Tag:TM(rTomm20),Tag:HA}, Scer\GAL4^Mef2.PR has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, Tfb4^KK107429, Tfb4^{UAS.N.Tag:FLAG} has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtDNA-helicase^{Δ1-33.UAS.Tag:TM(rTomm20),Tag:HA}, mtDNA-helicase^KK102418 has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtDNA-helicase^{Δ1-33.UAS.Tag:TM(rTomm20),Tag:HA} has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtDNA-helicase^KK102418, mtDNA-helicase^UAS.Tag:HA has visible | adult stage phenotype

(Shan et al., 2024)

MED8^KK107827, MED8^UAS.Tag:FLAG, Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtSSB^{Δ1-47.UAS.Tag:HA}, mtSSB^NIG.4337R has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, PolG2^{Δ1-20.UAS.Tag:TM(rTomm20),Tag:HA}, PolG2^GD4188, Scer\GAL4^Mef2.PR has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, PolG2^GD4188, PolG2^UAS.Tag:HA, Scer\GAL4^Mef2.PR has visible | adult stage phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtSSB^{Δ1-47.UAS.Tag:HA} has visible | adult stage phenotype

(Shan et al., 2024)

Phenotype Manifest In

Enhanced by

Statement

Reference

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, enhanceable by Rel^{UAS.cSa.Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Suppressed by

Statement

Reference

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible by MED8^KK107827, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible by PolG2^GD4188, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible by mtDNA-helicase^KK102418, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible by mtSSB^NIG.4337R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has mitochondrion phenotype, suppressible by MED8^KK107827, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has mitochondrion phenotype, suppressible by mtDNA-helicase^KK102418, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has mitochondrion phenotype, suppressible by PolG2^GD4188, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has mitochondrion phenotype, suppressible by Tfb4^KK107429, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has mitochondrion phenotype, suppressible by mtSSB^NIG.4337R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by mtSSB^{Δ1-47.Δ85-91.UAS.Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by PolG2^{Δ1-20.G31E.UAS.Tag:TM(rTomm20),Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by mtDNA-helicase^{Δ1-33.A442P.UAS.Tag:TM(rTomm20),Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by cGlr1^GD7883, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by Dredd^NIG.7486R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by Sting^NIG.1667R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by Rel^{Δ152-334.UAS.Tag:HA}, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by Rel^HM05154, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by Dref^NIG.5838R, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible | partially by PolrMT^HMS01474, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible by Hsap\MTERF4^UAS.Tag:HA, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype, suppressible by Tfb4^KK107429, Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Other

Statement

Reference

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtSSB^NIG.4337R, mtSSB^UAS.Tag:HA has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, PolG2^{Δ1-20.UAS.Tag:TM(rTomm20),Tag:HA}, Scer\GAL4^Mef2.PR has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, Tfb4^KK107429, Tfb4^{UAS.N.Tag:FLAG} has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtDNA-helicase^{Δ1-33.UAS.Tag:TM(rTomm20),Tag:HA}, mtDNA-helicase^KK102418 has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtDNA-helicase^{Δ1-33.UAS.Tag:TM(rTomm20),Tag:HA} has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtDNA-helicase^KK102418, mtDNA-helicase^UAS.Tag:HA has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtSSB^{Δ1-47.UAS.Tag:HA}, mtSSB^NIG.4337R has wing phenotype

(Shan et al., 2024)

MED8^KK107827, MED8^UAS.Tag:FLAG, Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, PolG2^{Δ1-20.UAS.Tag:TM(rTomm20),Tag:HA}, PolG2^GD4188, Scer\GAL4^Mef2.PR has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, PolG2^GD4188, PolG2^UAS.Tag:HA, Scer\GAL4^Mef2.PR has wing phenotype

(Shan et al., 2024)

Mterf4^NIG.15390R, Scer\GAL4^Mef2.PR, mtSSB^{Δ1-47.UAS.Tag:HA} has wing phenotype

(Shan et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Mterf4^NIG.15390R is rescued by Mterf4^UAS.Tag:HA/Scer\GAL4^Mef2.PR

(Shan et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

15390R-2

P{NIG.15390R}2

15390R-3

P{NIG.15390R}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG15390^NIG.15390R

Mterf4^NIG.15390R

Name Synonyms

Secondary FlyBase IDs

References (3)

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