FlyBase Allele Report: Dmel\esg[NIG.3758R]

General Information

Symbol

Dmel\esg^NIG.3758R

Species

D. melanogaster

Name

FlyBase ID

FBal0273944

Feature type

allele

Associated gene

Dmel\esg

Associated Insertion(s)

Carried in Construct

P{NIG.3758R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.3758R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-3758R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | spermatogenesis, with Scer\GAL4^C587, esg^HMS02538

(Kong et al., 2024)

decreased cell number | spermatogenesis, with Scer\GAL4^C587

(Kong et al., 2024)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^C587, esg^HMS02538, esg^NIG.3758R has abnormal cell number | spermatogenesis phenotype, suppressible by Scer\GAL4^C587/Socs36E^HMS01450

(Kong et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^C587, esg^HMS02538, esg^NIG.3758R has cyst progenitor cell | decreased number phenotype, suppressible by Scer\GAL4^C587/Socs36E^HMS01450

(Kong et al., 2024)

Scer\GAL4^C587, esg^HMS02538, esg^NIG.3758R has male germline stem cell | cell non-autonomous | decreased number phenotype, suppressible by Scer\GAL4^C587/Socs36E^HMS01450

(Kong et al., 2024)

Scer\GAL4^C587, esg^HMS02538, esg^NIG.3758R has germinal proliferation center hub phenotype, suppressible by Scer\GAL4^C587/Socs36E^HMS01450

(Kong et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

esg^NIG.3758R/esg^HMS02538 is rescued by esg^UAS.cFa/Scer\GAL4^C587

(Kong et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

NIG-Fly

3758R-1

P{NIG.3758R}1

3758R-5

P{NIG.3758R}5

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

esg^NIG.3758R

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close