FlyBase Allele Report: Mmus\Plpp3[UAS.GFP]

General Information

Symbol

Mmus\Plpp3^UAS.GFP

Species

M. musculus

Name

FlyBase ID

FBal0276704

Feature type

allele

Associated gene

Mmus\Plpp3

Associated Insertion(s)

Carried in Construct

P{UAS-mLPP3.GFP}

Transgenic product class

wild_type

(Ile et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Ile et al., 2012)

Mutagen

in vitro construct

(Ile et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-mLPP3.GFP}

Cytology

Description

UASt regulatory sequences drive expression of Mmus\Plpp3 which is tagged at the C-terminal end with GFP.

(Ile et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mmus\Plpp3

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

germline cell, with Scer\GAL4^da.G32

(Ile et al., 2012)

Detailed Description

Statement

Reference

Embryos expressing Mmus\Ppap2b^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^da.G32 have reduced numbers of germ cells due to germ cell death.

(Ile et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Mmus\Plpp3^UAS.GFP/Scer\GAL4^alrm.PD is a suppressor of abnormal neuroanatomy | larval stage phenotype of Df(2R)w45-19g, wun2^EP2650ex34, wun⁴⁹

(Chen et al., 2024)

Other

Statement

Reference

Df(2R)w45-19g, Mmus\Plpp3^UAS.GFP, Scer\GAL4^Tub.PU, wun2^EP2650ex34, wun⁴⁹ has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype

(Chen et al., 2024)

Phenotype Manifest In

Suppressor of

Statement

Reference

Mmus\Plpp3^UAS.GFP/Scer\GAL4^alrm.PD is a suppressor of embryonic/larval astrocyte-like glial cell | larval stage phenotype of Df(2R)w45-19g, wun2^EP2650ex34, wun⁴⁹

(Chen et al., 2024)

Other

Statement

Reference

Df(2R)w45-19g, Mmus\Plpp3^UAS.GFP, Scer\GAL4^Tub.PU, wun2^EP2650ex34, wun⁴⁹ has embryonic/larval astrocyte-like glial cell | larval stage | somatic clone - tissue specific phenotype

(Chen et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Expression of Mmus\Ppap2b^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^btl.PS rescues the tracheal defects that are seen in embryos lacking both maternal and zygotic wun and wun2 function.

(Ile et al., 2012)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mmus\Plpp3^{Scer\UAS.T:Avic\GFP}

Mmus\Plpp3^UAS.GFP

Mmus\Ppap2b^{Scer\UAS.T:Avic\GFP}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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