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General Information
Symbol
Dmel\pyrS0439
Species
D. melanogaster
Name
FlyBase ID
FBal0276773
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C11724348T

Reported nucleotide change:

C?T

Amino acid change:

Q117term | pyr-PB

Reported amino acid change:

Q117term

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: Q117term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

pyrS0439/pyrS3547 embryos show a mild defect in the migration of ventral astrocytes, while the infiltration of astrocyte processes into the neuropil is not significantly different from that of controls.

pyrS0439 mutant stage 17 embryos show a mild reduction in the number of longitudinal visceral muscle (LVM) fibres around the midgut, particularly in the anterior portion where LVM fibre spacing is wider and the first midgut constriction is either absent or reduced.

pyrS0439/Df(2R)BSC25 mutant stage 17 embryos show a strong reduction in the number of longitudinal visceral muscle (LVM) fibres around the midgut, particularly in the anterior portion where large areas are devoid of LVM fibres. The LVM founder cells are present at normal numbers in stage 11 embryos, but by stage 12 many of the founders have lost contact with the trunk visceral mesoderm (TVM) rather than spreading out across it. By stage 13 a large number of rounded and shrunken cells are seen some distance from the TVM.

pyrS0439/pyr18 mutant larval guts contain 5-8 longitudinal visceral muscle fibres per half side compared to 9-11 in wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

pyrS0439 has lethal | recessive phenotype, suppressible by Df(2R)ths238/+

pyrS0439 has lethal | recessive phenotype, suppressible by ths759/ths[+]

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)