FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\msl-3d01070
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General Information
Symbol
Dmel\msl-3d01070
Species
D. melanogaster
Name
FlyBase ID
FBal0276923
Feature type
allele
Associated gene
Dmel\msl-3
Associated Insertion(s)
P{XP}msl-3d01070
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Sinenko et al., 2010)
Progenitor genotype
Associated Insertion(s)
P{XP}msl-3d01070
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{XP}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  acute myeloid leukemia
      modeled by Hsap\RUNX1::Hsap\RUNX1T1UAS.cSa
      (Sinenko et al., 2010)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      One copy of msl-3d01070 has no effect on hemocyte proliferation in third instar larvae.

      (Sinenko et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      One copy of msl-3d01070 moderately suppresses the hemocyte overproliferation seen in third instar larvae when Hsap\RUNX1::Hsap\RUNX1T1Scer\UAS.cSa is expressed under the control of Scer\GAL4Hml.Δ.

      (Sinenko et al., 2010)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      msl-3d01070
      (Sinenko et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)