Imprecise excision of the progenitor insertion, resulting in a deletion which removes part of the Claspin gene (nucleotides +4299 to +5195 relative to the transcription start site are removed).
Deletion resulting from the imprecise excision of P{EP}GE20270, extending from +4299 to +5195, where +1 is the translation start of Claspin.
Eggs laid by homozygous females show a very low rate of hatching (0.7%). Most embryos laid by the mutant females show normal nuclear morphology until division 10, but after this stage defects in nuclear morphology begin to be seen. By division 13, less than one-third of the mutant embryos have normal nuclear morphology.
Homozygous animals show an increased frequency of generation of mutant clones compared to wild type in a loss of heterozygosity assay.
Ionising radiation-induced G2 arrest and apoptosis occur normally in homozygous eye discs.
Homozygous eye discs show defects in hydroxyurea-induced G2 arrest.
Homozygous larvae show reduced survival in the presence of hydroxyurea compared to wild type.
Claspinaq5 is a suppressor | partially of egg chamber phenotype of Rpp30k01901/Rpp3018.2