FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CRMPfs9a.EGFP
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General Information
Symbol
Dmel\CRMPfs9a.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0277235
Feature type
allele
Associated gene
Dmel\CRMP
Associated Insertion(s)
Carried in Construct
P{PYDGFPfs9a}
Key Links
Transgenic product class
frameshift_variant
(Morris et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
frameshift_variant
(Morris et al., 2012)
Mutagen
in vitro construct
(Morris et al., 2012)
Progenitor genotype
Carried in construct
P{PYDGFPfs9a}
Cytology
Description

10.9kb genomic fragment that spans CRMP, with a 26bp deletion introduced into alternative exon E9a; results in a frameshift in this exon. The coding sequence is tagged at the C-terminal end with EGFP.

(Morris et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
CRMP
Encoded product / tool
CRMP
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      larval central nervous system

      Comment: Expression specific to CRMP-RA.

      (Morris et al., 2012)
      Additional Information
      Statement
      Reference

      CRMPfs9a.T:AvicGFP-EGFP reflects the expression pattern of the CRMP-RA transcript isoform, and is expressed in the larval central nervous system.

      (Morris et al., 2012)
       
      Marker for
      Reflects expression of
      CRMP
      (Morris et al., 2012)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      CRMPfs9a.T:Avic\GFP-EGFP fails to support the suppression of the body colour phenotype of bunspecified, CRMPsupA4/CRMPsupK1 double mutants by rSu(b).cSa resulting in a dark gray cuticle.

      (Morris et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CRMPfs9a.EGFP
      CRMPfs9a.T:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)